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Patient Recruitment Case Study: Hepatic Encephalopathy

A phase 3 clinical trial evaluating rifaximin for the delay of encephalopathy decompensation in cirrhosis

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THE CLINICAL TRIAL
Decompensated cirrhosis is defined as an acute deterioration in liver function in a patient with cirrhosis and is characterized by jaundice, ascites, hepatic encephalopathy, hepatorenal syndrome or variceal haemorrhage. The purpose of the Red-C Studies was to see if an investigational drug given twice daily, will help delay the first episode of overt hepatic encephalopathy requiring hospitalization in patients with liver cirrhosis and how safe it is to use in people.

 

THE PROJECT
The Sponsor’s goal was to accelerate patient recruitment for this clinical study using a suite of patient recruitment materials developed by the Stark / Raving Health team. The program consisted of two global clinical studies, each with specific recruitment criteria. Our approach focused on establishing a unique study brand identity combined with recruitment and educational materials that engaged and empowered patients to consider participation.

Patient recruitment cirrhosis clinical study branding development
Patient recruitment cirrhosis clinical study branding development
Patient recruitment cirrhosis clinical study branding development

Study Branding

A strong study brand identity was essential for recruitment success as it differentiated the Red-C Studies from competing clinical trials, built trust with potential participants, and created a lasting impression among site staff. Our approached focused on creating a franchise-level brand for the program that was customized for each individual protocol.

Patient recruitment cirrhosis clinical study branding development
Patient recruitment cirrhosis clinical study branding and illustration services
Patient recruitment cirrhosis clinical study brand development and marketing
Patient recruitment cirrhosis clinical study branding and illustration services

Custom illustrations

An integral aspect of our creative strategy was the development of a unique visual identity that not only captured attention in clinical settings but also encourage potential participants to engage with the study team. Our in-house design team meticulously crafted a collection of custom illustrations that served as the cornerstone of the campaign, ensuring a consistent aesthetic across all countries involved in the studies.

Patient recruitment cirrhosis clinical study content creation
Patient recruitment cirrhosis clinical study marketing and advertising
Patient recruitment cirrhosis clinical study brand development and marketing

Content creation

Considering the symptoms of hepatic encephalopathy, which include cognitive impairment and difficulty concentrating, our content team took care to develop study materials that were easily accessible for this audience. Our focus on accessibility and health literacy ensured that interested patients had the materials they needed to make an informed decision to participate.

Patient recruitment cirrhosis clinical study content creation
Patient recruitment cirrhosis clinical study website design
Patient recruitment cirrhosis clinical study illustration and branding

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